Systematic reviews & systematic literature reviews

Systematic reviews (or systematic literature reviews) synthesise relevant studies that answer a specific research question (such as, ‘does this treatment work?’) and which have been identified based on pre-specified criteria.

Sometimes the results of studies included in a systematic review are statistically pooled in a meta-analysis. There are numerous types of systematic reviews (rapid, narrative, etc.) and meta-analyses (including network meta-analyses, and indirect treatment comparisons).

Our experience

We have conducted over 700 reviews and meta-analyses of therapeutic, screening and diagnostic interventions. These have covered a wide range of clinical topics using different types of systematic reviews and meta-analysis methods, and many have been published in top journals.

We are considered to be leaders in the area of systematic literature reviews, having contributed to methodological innovations such as QUADAS/QUADAS-2, ROBIS and PROBAST.

Identifying and synthesising the best available evidence

Why choose KSR?

Working with industry, academia, and government organisations, our reviews have supported policy making commissioning health services, and fourth hurdle processes (such as for NICE in the UK, or for IQWiG in Germany). We are also a ‘Centre of Excellence’ for Technology Assessment Reviews by the National Institute for Health Research (NIHR).

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Systematic reviews

Our experience

Identifying and synthesising the best available evidence

Why choose KSR?

Systematic reviews

Health technology assessments

Cost-effectiveness analyses

Clinical guidelines

Information specialist services

Training courses